CGSI

A presentation on statistical power and sample size determination.

CGSI 2026

Computational Methods in Genomic Technology Workshop Faculty Talk:

  • Title: Unveiling Complex Disease: From Network Analysis to Personalized Medicine
  • Location: Mong Auditorium, Engineering VI, 404 Westwood Plaza, Los Angeles, CA 90095
  • Date/Time: Monday, July 13th / 2:30 PM

  • Zhihan Zhang, Christiana Wang, Ziyin Zhao, Ziyue Yi, Arda Durmaz, Jennifer S. Yu, Gurkan Bebek. nSEA: n-Node Subnetwork Enumeration Algorithm Identifies Lower Grade Glioma Subtypes with Altered Subnetworks and Distinct Prognostics. Pacific Symposium on Biocomputing 29:521-533 (2024) (PMID: 38160304).

  • Durmaz A, Henderson TA, Brubaker D, Bebek G. Frequent Subgraph Mining of Personalized Signaling Pathway Networks Groups Patients With Frequently Dysregulated Disease Pathways and Predicts Prognosis. Pac Symp Biocomput. 2016;22:402-413 (PMCID: PMC6029858).

  • Bebek, G, Patel, V., Chance, M. Petals: PETALS: Proteomic Evaluation and Topological Analysis of a Mutated Locus’ Signaling. BMC Bioinformatics, 2010 Dec 13; 11:596. (PMCID: PMC3016410)

CGSI 2025

  • Title: Size Matters: Mastering Power and Sample Size
  • Location: Commons Auditorium, UCLA South Bay Campus, 30800 Palos Verdes Dr E, Rancho Palos Verdes, CA 90275
  • Date/Time: Saturday, July 12th / 10:45 AM – 11:15 AM

  • Zhao, S., Li, C.-I., Guo, Y., Sheng, Q., & Shyr, Y. (2018). RnaSeqSampleSize: real data based sample size estimation for RNA sequencing. BMC Bioinformatics, 19(1), 191. https://doi.org/10.1186/s12859-018-2191-5

  • Vieth, B., Ziegenhain, C., Parekh, S., Enard, W., & Hellmann, I. (2017). powsimR: Power analysis for bulk and single cell RNA-seq experiments. Bioinformatics, 33(21), 3486–3488. https://doi.org/10.1093/bioinformatics/btx435

  • Davis, A., Gao, R., & Navin, N. E. (2019). SCOPIT: sample size calculations for single-cell sequencing experiments. BMC Bioinformatics, 20(1), 566. https://doi.org/10.1186/s12859-019-3167-9

  • Kraemer HC, Mintz J, Noda A, Tinklenberg J, Yesavage JA. Caution Regarding the Use of Pilot Studies to Guide Power Calculations for Study Proposals. Arch Gen Psychiatry. 2006;63(5):484–489. https://doi.org/10.1001/archpsyc.63.5.484