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Bioinformatics & Biostatistics Core: Advanced Data Analysis Services

The Bioinformatics & Biostatistics Core is a collaborative center that provides investigators with bioinformatics expertise to analyze large molecular datasets and develop novel algorithms. Our mission is to support researchers by offering comprehensive analytical services, facilitating data-driven discoveries, and fostering long-term collaborations.

Our Expertise

We specialize in various domains, including:

• Genomics
• Transcriptomics
• Epigenomics
• Systems Biology
• Clinical Investigations

Our services include data analysis, systems analysis, biological interpretation, grant writing, and training. We offer exceptional fee-for-service computational analysis and algorithm development.

List of Services

Analytical Services

Transcriptomics

Techniques: RNA-Seq, miRNA-Seq, microarrays, single-cell RNA-Seq

• Study design, power calculations, alignment
• Gene-level or transcript-level quantification
• Differentially expressed gene lists
• Gene set enrichment analysis (GSEA)
• Gene set variation analysis (GSVA)
• Time series analysis, gene annotation, genome visualization
• Network/pathway analysis, integrative omics analysis for systems biology

Genomics

Techniques: Exome/Whole Genome Sequencing, SNP arrays, GWAS

• Study design, power calculations, alignment
• SNPs, indels, CNVs, structural variants, annotation
• Genome visualization, germline/somatic mutation calls
• Network analysis, integrative omics analysis for systems biology

Epigenomics

Techniques: ChIP-Seq, ATAC-Seq, methylation arrays, Bisulfite-Seq

• Study design, power calculations, alignment
• Peak calling, visualization, comparative analysis
• Motif search, integration with RNA data (optional)
• Differential methylation, network analysis

Metagenomics/Microbiome

Techniques: 16S rRNA-Seq, shotgun sequencing

• Study design, power calculations
• OTU picking, taxonomic abundance identification
• Alpha and beta diversity evaluation
• Network and pathway analysis

Proteomics

• Study design, power calculations
• Protein annotation, pathway/network analysis
• Time series analysis, phosphoproteomics analysis
• Protein set enrichment analysis, integrative omics analysis

Additional Services

Custom Analytical Pipelines & Algorithm Development

• Novel algorithms, custom analytical pipelines, custom integrative analyses

Network Analysis

• Protein-protein interactions, network propagation, data integration, subnetwork identification

Manuscript Preparation

• Ongoing support for drafting and revising manuscript text, figures, and methods

Proposal Consultations and Preparation

• Methods development, power calculations, preliminary data analysis, grant review

Data Management

• Data storage (AWS or HPC on campus), GEO, or other public repository upload

Rates

The initial consultation (up to 30 minutes) is free of charge. After the consultation, projects are charged at an hourly rate as follows:

After the consultation, we provide an estimated number of hours required, a quote, and a project start date. You will receive detailed monthly billing updates and ongoing analysis results via our project page throughout the project.

For inquiries and consultation scheduling, please contact us.